The Penny Arcade cartoon strip is on hundreds and thousands of gamers' radar. Recently, the site created the http://www.penny-arcade.com/childsplay/Child's Play campaign, which invites members of its reader community to donate games and other items (including DVDs, books, and toys) to children being treated at Seattle Childrens Hospital.
Penny Arcade introduced Child's Play the week before Thanksgiving, but if you missed the post and would like to know more about the program, a good place to start is the link noted above. GameSpot encourages readers to have a look at the program and what it is trying to accomplish--and consider its well-intended message.